Retrieval of Extruded Mineral Trioxide Aggregate Using a Novel Suction Device.

Retrieval of Extruded Mineral Trioxide Aggregate Using a Novel Suction Device.

Treatment of necrotic immature eternal tooth is an exigently demanding state of affairs for an endodontist. Regenerative endodontic procedures are being employed for such tooth in a hope to revive a sensible pulp tissue and proceed root enchancment. Nonetheless, in the meanwhile advocated strategies might be not environment friendly in retaining mineral trioxide combination (MTA)…

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Arsenic trioxide as a novel anti-glioma drug: a review

Arsenic trioxide as a novel anti-glioma drug: a review

Arsenic trioxide has proven a robust anti-tumor impact with little toxicity when used within the therapy of acute promyelocytic leukemia (APL). An impact on glioma has additionally been proven. Its mechanisms embody regulation of apoptosis and autophagy; promotion of the intracellular manufacturing of reactive oxygen species, inflicting oxidative harm; and inhibition of tumor stem cells.…

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A Systematic Review Comparing Mineral Trioxide Aggregate to Other Commercially Available Direct Pulp Capping Agents in Dogs

A Systematic Review Comparing Mineral Trioxide Aggregate to Other Commercially Available Direct Pulp Capping Agents in Dogs

Very important pulp remedy (VPT) and direct pulp capping (DPC) are procedures repeatedly carried out in canine for the administration of acute tooth fractures and as a part of administration for traumatic malocclusions. The aim of this assessment is to use an evidence-based medication strategy to systematically assessment and consider the scientific literature evaluating the…

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Efficacy and Tolerability of First Line Arsenic Trioxide in Combination With All-Trans Retinoic Acid in Patients With Acute Promyelocytic Leukemia: Real Life Experience

Efficacy and Tolerability of First Line Arsenic Trioxide in Combination With All-Trans Retinoic Acid in Patients With Acute Promyelocytic Leukemia: Real Life Experience

Acute promyelocytic leukemia is a variant of acute myeloid leukemia characterised by t(15;17) and PML/RAR alfa fusion gene. The invention of the molecular pathogenesis has led to entitle all-trans retinoic acid (ATRA) as the primary focused remedy for acute leukemia. It’s often related to anthracycline-based chemotherapy with excessive response charges, however potential long-term sequelae together…

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Arsenic trioxide enhances the chemotherapeutic efficiency of cisplatin in cholangiocarcinoma cells via inhibiting the 14-3-3ε-mediated survival mechanism

Arsenic trioxide enhances the chemotherapeutic efficiency of cisplatin in cholangiocarcinoma cells via inhibiting the 14-3-3ε-mediated survival mechanism

Cholangiocarcinoma (CCA) is the second most frequent main liver carcinoma with excessive levels of malignancy and mortality. Chemotherapy performs a key position within the remedy of CCA, nonetheless, the low chemotherapeutic effectivity results in a bottleneck. So unraveling the potential mechanisms to reinforce the effectivity (lowered the dosage and enhanced the consequences of chemotherapy medicine)…

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Metabolic adaptation drives arsenic trioxide resistance in acute promyelocytic leukemia

Molybdenum Trioxide purified Antimony Trioxide extrapurified AR Molybdenum Trioxide extrapurified AR Pyridine-Sulfur Trioxide Complex Lead Titanium Trioxide Sulfur Trioxide Pyridine Complex

Acquired genetic mutations can confer resistance to arsenic trioxide (ATO) within the remedy of acute promyelocytic leukemia (APL). Nonetheless, such resistance-conferring mutations are uncommon and don’t clarify most illness recurrence seen within the clinic. Now we have generated secure ATO-resistant promyelocytic cell strains which are additionally much less delicate to ATRA and the mix of…

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