Arsenic trioxide as a novel anti-glioma drug: a review

Arsenic trioxide as a novel anti-glioma drug: a review

Arsenic trioxide has proven a robust anti-tumor impact with little toxicity when used within the therapy of acute promyelocytic leukemia (APL). An impact on glioma has additionally been proven. Its mechanisms embody regulation of apoptosis and autophagy; promotion of the intracellular manufacturing of reactive oxygen species, inflicting oxidative harm; and inhibition of tumor stem cells.…

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