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Molybdenum Trioxide purified Antimony Trioxide extrapurified AR Molybdenum Trioxide extrapurified AR Pyridine-Sulfur Trioxide Complex Lead Titanium Trioxide Sulfur Trioxide Pyridine Complex
Elijah
- 0
Acquired genetic mutations can confer resistance to arsenic trioxide (ATO) within the remedy of acute promyelocytic leukemia (APL). Nonetheless, such resistance-conferring mutations are uncommon and don’t clarify most illness recurrence seen within the clinic.
Now we have generated secure ATO-resistant promyelocytic cell strains which are additionally much less delicate to ATRA and the mix of ATO and ATRA in comparison with the delicate cell line.
Characterization of those in-house generated resistant cell strains confirmed important variations in immunophenotype, drug transporter expression, anti-apoptotic protein dependence, and PML-RARA mutation. Gene expression profiling revealed outstanding dysregulation of the mobile metabolic pathways in these ATO resistant APL cell strains.
Glycolytic inhibition by 2-DG was enough and corresponding to the usual of care (ATO) in focusing on the delicate APL cell line. 2-DG was additionally efficient within the in vivo transplantable APL mouse mannequin; nevertheless, it didn’t have an effect on the ATO resistant cell strains. In distinction, the resistant cell strains had been considerably affected by compounds focusing on the mitochondrial respiration when mixed with ATO, regardless of the ATO resistance-conferring genetic mutations or the sample of their anti-apoptotic protein dependency.
Our information exhibit that the addition of mitocans together with ATO can overcome ATO resistance. We additional present that this mixture has the potential within the remedy of non-M3 AML and relapsed APL. The interpretation of this strategy within the clinic must be explored additional.
Colorimetric Comparability of Inside Bleaching with and with out Eradicating Mineral Trioxide Mixture (MTA) on Induced Coronal Tooth Discoloration by MTA
This examine aimed to colorimetric comparability of inner bleaching with and with out eradicating mineral trioxide combination (MTA) on induced coronal tooth discoloration by MTA cement. On this experimental examine, twenty human tooth had been ready.
An OrthoMTA barrier was positioned 1 mm beneath the CEJ. The tooth had been restored with composite resin and had been positioned within the ageing accelerator machine. Then, the specimens had been divided into two teams (n = 10); in group A, a part of the OrthoMTA was eliminated and the glass ionomer was positioned on the OrthoMTA, and in group B, the OrthoMTA remained intact. Inside bleaching was carried out 5 instances in 6-day intervals utilizing 37% carbamide peroxide gel.
Coloration dedication was carried out in 5 phases: baseline, after OrthoMTA discoloration, earlier than OrthoMTA elimination, after OrthoMTA elimination, and after bleaching remedy periods. In group A, eight specimens reached to ∆E < 3.Three after 2 instances inner bleaching remedy, and in group B, 5 specimens reached to ∆E < 3.Three with nearly Three bleaching periods (p > 0.05).
Moreover, 5 specimens reached to the preliminary colour (baseline) after bleaching remedy, Four specimens in group A and 1 specimen in group B. After OrthoMTA elimination, 2 specimens in group A reached to ∆E < 3.3. There was no important distinction between teams with or with out OrthoMTA elimination (p=0.06). Though, the specimens with OrthoMTA elimination required fewer bleaching remedy periods, and the imply worth of ∆E was decrease on this group.

Iridium in Tungsten Trioxide Matrix as an Environment friendly Bi-Purposeful Electrocatalyst for General Water Splitting in Acidic Media
Electrocatalytic water splitting in acidic media is a promising technique for grid scale manufacturing of hydrogen utilizing renewable power, however challenges nonetheless exist within the growth of superior catalysts with each excessive exercise and stability.
Herein, it’s reported that iridium doped tungsten trioxide (Ir-doped WO3 ) with arrayed construction and confined Ir websites is an environment friendly and sturdy bi-functional catalyst for general acidic water splitting. A low overpotential (258 mV) is required to realize an oxygen evolution response present density of 10 mA cm-2 in 0.5 m H2 SO4 answer.
In the meantime, Ir-doped WO3 processes the same intrinsic exercise to Pt/C towards hydrogen evolution response. General water splitting utilizing the bi-functional Ir-doped WO3 catalyst exhibits low cell voltages of 1.56 and 1.68 V to drive the present densities of 10 and 100 mA cm-2 , respectively, with solely 16 mV decay noticed after 60 h steady electrolysis underneath the present density of 100 mA cm-2 . Structural evaluation and density useful idea calculation point out that the adjusted coordination setting of Ir inside the crystalline matrix of WO3 contributes to the excessive exercise and sturdiness.
Pulpal response to mineral trioxide combination containing phosphorylated pullulan-based capping materials
This examine aimed to judge the pulpal responses of monkey’s pulp after direct pulp capping (DPC) with the novel mineral trioxide combination containing phosphorylated pullulan-based materials (MTAPPL). Seventy-two tooth had been randomly divided into 4 teams: MTAPPL; Nex-Cem MTA (NX);
TheraCal LC (TH); and Dycal (DY). Histopathological adjustments within the pulps had been noticed at days 3, 7 and 70. On day 3, delicate inflammatory responses had been noticed within the MTAPPL, no to reasonable inflammatory responses within the TH, whereas reasonable inflammatory responses within the NX and DY. No mineralized tissue formation (MTF) was noticed in all teams.
On day 7, no or delicate inflammatory responses had been noticed in all teams. Preliminary MTF was noticed aside from DY. No irritation with full MTF together with presence of odontoblast-like cells was noticed within the MTAPPL, NX and TH teams at day 70. These findings point out that MTAPPL might be an environment friendly DPC materials.
Liquiritigenin protects towards arsenic trioxide-induced liver damage by inhibiting oxidative stress and enhancing mTOR-mediated autophagy
Liquiritigenin (LQ) has protecting results towards varied hepatotoxicities. Nonetheless, its particular position on arsenic trioxide (ATO)-induced hepatotoxicity and the associated biomolecular mechanisms stay unclear.
The aim of this examine is to discover the protecting actions of LQ on ATO-induced hepatotoxicity and its biomolecular mechanisms in mice. LQ was administered orally at 20 and 40 mg/kg per day for seven consecutive days with an intraperitoneal injection of ATO (5 mg/kg). Liver damage was induced by ATO and was alleviated by remedy with LQ as mirrored by diminished histopathological injury of liver and decreased serum ALT, AST, and ALP ranges.
The era of intracellular ROS induced by ATO was attenuated after LQ remedy. The degrees of SOD, CAT, and GSH had been elevated with LQ administration whereas MDA ranges decreased. LQ mitigated elevated TNF-α and IL-6 ranges in addition to the hepatic mitochondrial injury brought on by ATO. Furthermore, LQ upregulated the expression of LC3-II and enhanced autophagy within the liver of ATO-induced mice. Additional research indicated that LQ considerably suppressed the expression of p-PI3K, p-AKT, and p-mTOR in ATO-induced mice.
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Molybdenum(VI) oxide, 99.9% |
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Molybdenum(VI) oxide, 99.0% |
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Molybdenum(VI) oxide, 99.9% |
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Molybdenum(VI) oxide, 99.9% |
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Molybdenum Foil 0.25mm, 99.9+% |
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Molybdenum Foil 0.25mm, 99.9+% |
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Molybdenum Foil 0.025mm, 99.9+% |
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Molybdenum(IV) sulfide, 98+% |
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ICP Std Molybdenum 10000ug/mL in 2% NH4OH |
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ICP Std Molybdenum 100ug/mL in 2% NH4OH |
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Molybdenum Rod 10 mm diameter, 99.95% |
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Molybdenum Rod 20 mm diameter, 99.9+% |
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Molybdenum Wire 0.3 mm diameter, 99.95% |
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Molybdenum Wire 0.25 mm diameter, 99.95% |
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Molybdenum Wire 0.7 mm diameter, 99.95% |
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Molybdenum Wire 0.1 mm diameter, 99.95% |
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Molybdenum Wire 0.5 mm diameter, 99.95% |
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Molybdenum Wire 2.0 mm diameter, 99.95% |
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Molybdenum Wire 1.5 mm diameter, 99.95% |
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GX0574-1 | Glentham Life Sciences | 1 | EUR 99.4 |
Molybdenum Wire 1.5 mm diameter, 99.95% |
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Molybdenum Powder max. 100 micron, 99.9% |
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Molybdenum Powder max. 100 micron, 99.9% |
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ICP Std Molybdenum 1000ug/mL in 2-5% HNO3 tr. HF |
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PMO2A10 | Scientific Laboratory Supplies | 100ML | EUR 246.76 |
ICP Standard Molybdenum H2O 1000ug/ml |
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Molybdenum Foil 0.1 mm, plane, shiny, 99.95% |
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GX4593-100 | Glentham Life Sciences | 100 | EUR 180.9 |
molybdenum cofactor sulfurase Antibody |
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E300911 | EnoGene | 200ul | EUR 275 |
Description: Available in various conjugation types. |
Molybdenum(IV) disulfide Nanopowder, 99 % |
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GX4987-10 | Glentham Life Sciences | 10 | EUR 311.3 |
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GX4987-25 | Glentham Life Sciences | 25 | EUR 593.2 |
Molybdenum Cofactor Synthesis 2 Protein |
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20-abx263321 | Abbexa |
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Arsenic Trioxide Standard 100ppm |
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AR2O3-CO | Scientific Laboratory Supplies | 1L | EUR 266.4 |
SULFUR TRIOXIDE PYRIDINE COMPLEX |
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719008 | Survival Technologies | each | Ask for price |
Molybdenum Cofactor Sulfurase (MOCOS) Antibody |
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20-abx113870 | Abbexa |
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Molybdenum 1000 ug/g (1000 PPM) for AA and ICP 50 grams in Base Oil 75 |
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Molybdenum Pellets‚6.35 x 6.35 mm, vacuum melted, 99.98% |
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GX9003-100 | Glentham Life Sciences | 100 | EUR 293.3 |
Molybdenum Pellets‚6.35 x 6.35 mm, vacuum melted, 99.98% |
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GX9003-25 | Glentham Life Sciences | 25 | EUR 119.1 |
Molybdenum Cofactor Synthesis 2 (MOCS2) Antibody |
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20-abx135733 | Abbexa |
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Molybdenum Cofactor Synthesis 2 (MOCS2) Antibody |
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abx235264-100ug | Abbexa | 100 ug | EUR 577.2 |
Molybdenum Cofactor Synthesis 2 (MOCS2) Antibody |
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20-abx321401 | Abbexa |
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Molybdenum Cofactor Synthesis 2 (MOCS2) Antibody |
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20-abx321402 | Abbexa |
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Molybdenum Cofactor Synthesis 1 (MOCS1) Antibody |
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20-abx321947 | Abbexa |
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Molybdenum Cofactor Synthesis 1 (MOCS1) Antibody |
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20-abx322547 | Abbexa |
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Molybdenum Cofactor Synthesis 2 (MOCS2) Antibody |
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20-abx113871 | Abbexa |
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Molybdenum Cofactor Synthesis 1 (MOCS1) Antibody |
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abx025653-400ul | Abbexa | 400 ul | EUR 627.6 |
Molybdenum Cofactor Synthesis 1 (MOCS1) Antibody |
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abx025653-80l | Abbexa | 80 µl | EUR 343.2 |
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abx036894-100ug | Abbexa | 100 ug | EUR 469.2 |
Molybdenum Cofactor Synthesis 2 (MOCS2) Antibody |
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abx028710-400ul | Abbexa | 400 ul | EUR 627.6 |
Molybdenum Cofactor Synthesis 2 (MOCS2) Antibody |
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abx028710-80l | Abbexa | 80 µl | EUR 343.2 |
Molybdenum Cofactor Synthesis 1 (MOCS1) Antibody |
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abx037731-100ug | Abbexa | 100 ug | EUR 469.2 |
Molybdenum Cofactor Synthesis 1 (MOCS1) Antibody |
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20-abx131326 | Abbexa |
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Molybdenum Cofactor Synthesis 1 (MOCS1) Antibody |
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20-abx131327 | Abbexa |
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Molybdenum Cofactor Synthesis 1 (MOCS1) Antibody |
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20-abx005887 | Abbexa |
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Molybdenum Cofactor Synthesis 2 (MOCS2) Antibody |
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20-abx304514 | Abbexa |
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Kinesis Hollow Cathode Lamp Molybdenum 37mm Std |
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CHR5781 | Scientific Laboratory Supplies | EACH | EUR 334.23 |
Cow Molybdenum cofactor sulfurase (MOCOS) ELISA Kit |
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abx516487-96tests | Abbexa | 96 tests | EUR 1093.2 |
ELISA kit for Human Molybdenum cofactor sulfurase |
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EK3232 | SAB | 96 tests | EUR 663.6 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Molybdenum cofactor sulfurase in samples from serum, plasma, tissue homogenates and other biological fluids. |
Recombinant Molybdenum Cofactor Synthesis 1 (MOCS1) |
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4-RPC623Hu01 | Cloud-Clone |
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Description: Recombinant Human Molybdenum Cofactor Synthesis 1 expressed in: E.coli |
Recombinant Molybdenum Cofactor Synthesis 1 (MOCS1) |
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4-RPC623Mu01 | Cloud-Clone |
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Description: Recombinant Mouse Molybdenum Cofactor Synthesis 1 expressed in: E.coli |
Recombinant Molybdenum Cofactor Synthesis 2 (MOCS2) |
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RPU58209-100ug | Biomatik Corporation | 100ug | EUR 537.6 |
Recombinant Molybdenum Cofactor Synthesis 2 (MOCS2) |
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RPU58209-1mg | Biomatik Corporation | 1mg | EUR 2496 |
Recombinant Molybdenum Cofactor Synthesis 2 (MOCS2) |
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RPU58209-50ug | Biomatik Corporation | 50ug | EUR 418 |
Recombinant Molybdenum Cofactor Synthesis 2 (MOCS2) |
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RPU57421-100ug | Biomatik Corporation | 100ug | EUR 470.4 |
Recombinant Molybdenum Cofactor Synthesis 2 (MOCS2) |
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RPU57421-1mg | Biomatik Corporation | 1mg | EUR 2184 |
Recombinant Molybdenum Cofactor Synthesis 2 (MOCS2) |
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RPU57421-50ug | Biomatik Corporation | 50ug | EUR 385 |
Recombinant Molybdenum Cofactor Synthesis 1 (MOCS1) |
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RPU51567-100ug | Biomatik Corporation | 100ug | EUR 492.8 |
Recombinant Molybdenum Cofactor Synthesis 1 (MOCS1) |
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RPU51567-1mg | Biomatik Corporation | 1mg | EUR 2184 |
Recombinant Molybdenum Cofactor Synthesis 1 (MOCS1) |
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RPU51567-50ug | Biomatik Corporation | 50ug | EUR 396 |
Recombinant Molybdenum Cofactor Synthesis 1 (MOCS1) |
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RPU53601-100ug | Biomatik Corporation | 100ug | EUR 554.4 |
Recombinant Molybdenum Cofactor Synthesis 1 (MOCS1) |
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RPU53601-1mg | Biomatik Corporation | 1mg | EUR 2457 |
Recombinant Molybdenum Cofactor Synthesis 1 (MOCS1) |
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RPU53601-50ug | Biomatik Corporation | 50ug | EUR 445.5 |
Kinesis Hollow Cathode Lamp Molybdenum 37mm unicam |
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CHR5785 | Scientific Laboratory Supplies | EACH | EUR 385.15 |
Kinesis Hollow Cathode Lamp Molybdenum 37mm Varian |
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CHR5787 | Scientific Laboratory Supplies | EACH | EUR 385.15 |
Human Molybdenum cofactor sulfurase (MOCOS) ELISA Kit |
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abx250798-96tests | Abbexa | 96 tests | EUR 801.6 |
Mouse Molybdenum cofactor sulfurase (MOCOS) ELISA Kit |
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abx516489-96tests | Abbexa | 96 tests | EUR 886.8 |
Molybdenum Cofactor Synthesis 2 (MOCS2) Antibody (HRP) |
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20-abx304515 | Abbexa |
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Mouse Mocos/ Molybdenum cofactor sulfurase ELISA Kit |
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E0967Mo | Sunlong | 1 Kit | EUR 758.4 |
Human MOCOS/ Molybdenum cofactor sulfurase ELISA Kit |
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E1626Hu | Sunlong | 1 Kit | EUR 726 |
Human MOCOS(Molybdenum cofactor sulfurase) ELISA Kit |
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EH1514 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human Molybdenum cofactor sulfurase, MOCOS ELISA KIT |
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ELI-20833h | Lifescience Market | 96 Tests | EUR 988.8 |
Mouse Molybdenum cofactor sulfurase, Mocos ELISA KIT |
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ELI-16543m | Lifescience Market | 96 Tests | EUR 1038 |
Mouse Molybdenum cofactor sulfurase (MOCOS) ELISA Kit |
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RK13536 | Abclonal | 96T | EUR 280 |
Human Molybdenum cofactor sulfurase (MOCOS) ELISA Kit |
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RK11526 | Abclonal | 96T | EUR 280 |
Human Molybdenum Cofactor Synthesis 1 (MOCS1) Protein |
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20-abx650079 | Abbexa |
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Mouse Molybdenum Cofactor Synthesis 1 (MOCS1) Protein |
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20-abx650080 | Abbexa |
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Kinesis Hollow Cathode Lamp Molybdenum 50mm Standard |
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CHR5789 | Scientific Laboratory Supplies | EACH | EUR 438.68 |
Molybdenum Cofactor Synthesis 2 (MOCS2) Antibody (FITC) |
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20-abx304516 | Abbexa |
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Bovine MOCOS/ Molybdenum cofactor sulfurase ELISA Kit |
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E0183Bo | Sunlong | 1 Kit | EUR 860.4 |
Bovine Molybdenum cofactor sulfurase, MOCOS ELISA KIT |
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ELI-19415b | Lifescience Market | 96 Tests | EUR 1113.6 |
Bovine Molybdenum cofactor sulfurase (MOCOS) ELISA Kit |
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RK15155 | Abclonal | 96T | EUR 280 |
Molybdenum Cofactor Synthesis 2 (MOCS2) Antibody (Biotin) |
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20-abx304517 | Abbexa |
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Human Molybdenum Cofactor Synthesis 2 (MOCS2) ELISA Kit |
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abx381488-96tests | Abbexa | 96 tests | EUR 1093.2 |
SULFUR TRIOXIDE DIMETHYL FORMAMIDE COMPLEX |
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919007 | Survival Technologies | each | Ask for price |
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In conclusion, our findings present that LQ protects towards ATO-induced hepatotoxicity as a consequence of its antioxidant and anti inflammatory actions and enhancement of autophagy mediated by the PI3K/AKT/mTOR signaling pathway in mice.
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